Heather of Infinite Bits tracks The Blob, from 1958 movie to Dutch student project to Wii game.
"Perhaps the biggest difference I found in comparing the two incarnations of the game is the motivation of the Blobs. In de Blob, the Blob must save the citizens of Chroma City.
The Blob (original game), on the other hand, takes a lot of inspiration from the classic 1958 horror movie of the same name. In this game he's absorbing people, rather than saving them. I think the original blob is a bad guy. And I like that; I so rarely get to be the bad guy..."