GameZone writes: "Radical Entertainment, the developer of The Incredible Hulk: Ultimate Destruction and Crash of the Titans, returns back to the Crash Bandicoot franchise with Crash: Mind Over Mutant. If you've lost count, this happens to be the 15th installment in the Crash series and seemingly has gained some of its lost luster. Mind Over Mutant takes over where Crash of the Titans left off as it's a true sequel to its predecessor.
Dr. Neo Cortex and Dr. Nitrus Brio are back as the antagonists as they run amok as they attempt to ruin Crash's life by taking control over people through a device that's similar to a cellular phone. Of course Crash is the only one not harmed by the device, so it's up to him to stop their devious plans and you should know the rest if you've played a Crash game previously."