Metal Gear Solid 4 will get a Trophy patch, according to an interview with Hideo Kojima in this week's Famitsu. The magazine does not reveal a date for the patch, but MGS4 is scheduled to receive a budget release in in August, so the timing could coincide with that.
Update "This report does appear to be true. The Trophy support will be included out the box with a 3,990 yen "PlayStation 3 The Best" budget version of MGS4 in August. Current MGS4 owners will be able to patch their copy of the game."