Running away is highly recommended in Downpour. Enemies are tough and aggressive and take quite a few hits to go down. If you leave them in this state, they will be stunned for a while. You can finish them off, but situations are almost always designed so that this is not a necessity. Available weapons are sourced from the environment, with a small selection of firearms throughout the game. Hefting a gun may sound like an assuring safety net, but bullets are scarce and they are often rendered useless during the tight, fast moving encounters.