GR - "There are numerous settings in which Assassin's Creed III can take place. We've picked five eras in which the next great Assassin would be best suited to haunt."
How about they set it where desmond left off at the end of revelation, since ubisoft said this is the end of desmonds story ark and he got all the clues from the previous 4 games. I don't personally see him going back into the animus since it just nearly killed him and it led him to where he needs to be. My two cents is present day.
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