In a recent interview with UGDB, Phil Marineau the Senior Brand Manager at Visceral Games is talking about pretty much everything related to Dante's Inferno:
"UGDB: One of the main problems of modern games is the unbelievably long loading times, which can be really annoying and frustrating for every player. Will Dante's Inferno have any such long loading times?
PM: There is no loading in the game! Dante wrote about this idea that you are always descending, you are always going down and we decided that we want to have that feeling in the game as well."