1UP writes: "Given the surge in popularity of the "tower defense" genre, it can be difficult for new releases to distinguish themselves in the crowded, if still niche space. On the surface, South Park: Let's Go Tower Defense Play! might seem like an odd pairing of genre and license, but if the peanut butter and banana sandwich taught us anything, it's that two distinct ingredients can combine and complement one another to create a unique product. Announced at last year's E3 as a Live Arcade exclusive, South Park LGTDP! is a competent tower defense game that will shine for fans of co-op gameplay and the irreverent cartoon series."