Even if you manage to adjust to the controls, Deep Space Rescue has other problems that discourage replay. The game doesn't save your progress when exiting, because it's only three missions long. You can finish the entire game in literally ten minutes. One mission doesn't even feature any combat.
Amazingly, these three missions are riddled with bugs, including a final boss battle in which the alien just stands still, letting you fill her up with bullets. Objects frequently rest in walls. It's even possible to get stuck in a wall yourself, at which point you have to ask: who exactly needs rescuing?