GamingFront: There are downsides to Prototype for example like the sometimes tricky targeting system locks on to stuff that you don't want it to lock on and the horrible camera angles at times. A problem that frustrated a lot is the lack of any multiplayer modes what so ever. I didn't mind it but if you're a multiplayer buff then it might be a drawback.
Overall Prototype is a great sandbox-style action game that is easily one of summers must have games. You won't be disappointed and it will be worth every penny. It's a must play game.