Resident Evil 5 has huge shoes to fill. No doubt about it. Resident Evil 4 was one of the "it" games of the last generation of consoles when it debuted on the Gamecube. It sold so well, Capcom re-released the game on the PS2 and that sold huge numbers as well. RE4 was so popular that it influenced the next generation of shooters like Gears of War and every third person shooter that followed it. So, there's no where to go, but down.