''When Trauma Center: Under the Knife 2 was announced earlier this year, I was pretty excited. I have been a fan of this series since its DS roots, and while I enjoyed the Wii installments in the franchise, I can't say I was as attached the new characters as I was to Dr. Derek Stiles and his assistant, Nurse Angie. I was thrilled to hear that they would be returning in a direct sequel to the first game in the series, although I was also wary that the game would run into some old issues upon its homecoming. While the game is definitely not perfect, it is a solid entry in a fun series that has always offered a unique gaming experience.
Story-wise, the game is a sequel in every possible way, bringing back many of the characters from the first Under the Knife, and referencing many of its important plot points. While the last Trauma Center game, New Blood for the Wii, took itself a little too seriously, I was happy to find that Under the Knife 2 has more of a silly, purposely over-the-top tone just as the first game did. I was a bit disappointed that the storyline was basically just a copy-and-paste of the first game, however; I expected many of the same operations, but when GUILT returned, I can't say I was overjoyed. They couldn't have at least come up with a new disease?''