It's time to load up the shotgun and lace up your good running shoes, because it's happened. A mutated strand of the rabies virus has nearly eradicated the human species, turning former friends and family into blood thirsty cannibalistic mindless killing machines; the infected, for short. There are hundreds, if not thousands if these things roaming the street looking for some fresh meat to tear into. Your meat to be precise. Now it's up to you and a small band of survivors to try and escape from the city where you've been Left 4 Dead!