This week IGN received a great bounty -- Mass Effect! After spending all night playing BioWare's epic RPG, the Xbox Team (Hilary Goldstein, Erik Brudvig, and Nate Ahearn) gathered for a podcast to offer impressions and answer your questions. Many, many Mass Effect questions answered. Do not listen unless you want to get pumped for this game!
The podcast is 1 hour and 12 minute. Reader Q&A segment begins at 35:10. The answers are very in-depth and cover a lot of grounds and details. May contain spoilers.
See the first comment below for highlights from the first 35 minutes of the podcast (before Q&A,) and the second comment for a listing of the questions emailed in by IGN readers.