According to one of the members of DotA 2 staff, in case you can run Alien Swarm, you will be able to run DotA 2 since both games require same System specs to be played.
So basically if you've bought a computer in the last 5 years....you can max this out is what I'm seeing (granted it's 1 am and I need to go to bed but don't worry about that)
Wow, a new game my PC will run?
I guess mac specs are more or less the same? or has it been canceled?
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