From Xbox360Fanboy.com : "Dead Rising is DOA on my 360. I loaded the menu ok, but when I tried to start the game, it smacked me with a disc read error, despite being a pristine new copy. The usual "clear the cache' tricks didn't help. But, as suspected, when I removed the hard drive, things worked fine. It turns out plenty of other deadly pissed off customers have a reason to stumble back to the mall with receipt in hand"