G4: "After finishing work on the supercharged, open-world, action-fest Prototype, the developers at Radical Entertainment took a good hard look at what fans and critics alike had to say about the game. Taking the good with the bad, the team used the game’s somewhat mixed reception as a launching pad to begin work on Prototype 2. And launch they did.
The game is set in New York City, only thanks the devastation that has befallen it, it is now known as New York Zero (no calories, but a lot more death), and it’s been divided into three islands in varying states of decay. Manhattan has been classified as the Red Zone, and has become overrun and overgrown by viral organisms, essentially making a disease-ridden urban jungle."