2011 is not even halfway over, but the list of interesting video game character is already pretty significant. Here is a list BrutalGamer.com's most interesting and memorable video game characters to date (as of June 2011).
Warning: The following article contains spoilers for the following games: Bulletstorm, Dead Space 2, and Portal 2. Proceed with caution.
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Of the list Sarrano was my favorite, but because he's so filthy-mouthed, I think Cave has to take the overall win.