Christian Gyrling, AI and Animation Programmer of Uncharted: Drake's Fortune, gives some insight into the development process in creating the game's characters:
"The final AI in Uncharted is simple, yet also very powerful. We are heavily utilizing the Cell architecture to allow the enemies to be more aware of their surroundings. On top of this, the AI is highly configurable to allow the designers to create custom behaviors. Examples of this are combat distance used for close-combat/ranged enemies, likelihood of moving and reaction times, grenade throwing and shooting styles. The goal was to make the AI 'seem' smart. If we could do so without making the code complex, that would be great. The approach we took to this was to use animations to add variations to our characters instead of trying to programmatically add complex behaviors."