No Mutants Allowed (NMA) has the highlights of forum Q&As based on their recent demo session of Fallout 3 and Q&A with Peter Hines up on their blog. Part five of the series covers voice acting and interface issues. There were also quite a few questions fielded on NPCs in Fallout 3 particularly in comparison with Oblivion.
Part five of this series as well as the first four installments can be accessed for Fallout 3 A Post Nuclear Blog.
(All 5 parts are listed under Alternative Sources. The main source link directs to Part 5.)