GameStooge had some hands-on time with Guild Wars 2 at New York Comic Con and was thoroughly impressed with it.
Excerpt: "After choosing a race, class and editing their appearance, you are asked a series of multiple choice questions about their background and personality. Some of the answers have a direct effect on the skill set, while others affect the story itself. The gaming experience will change depending on what the player chose. One may take a human male necromancer two different times, but can have different experiences. A noble will view things from one perspective, while a character from a farming background will have another. In addition, decisions made during the game affect the experience even more – do you stop to instruct farmers under attack to run to the inn, or do you just make a beeline to the inn yourself, leaving the farmers alone? Decisions made earlier in the game have repercussions later, much like a BioWare or Obsidian RPG."