GameSpot writes: "As a romantic comedy, Runaway: A Twist of Fate works pretty well. As an adventure game, not so much. Pendulo Studios' final chapter in the trilogy recounting the travails of lovable goofball Brian Basco and his erstwhile girlfriend, Gina Timmins, sacrifices gameplay for a whole lot of story in this mostly traditional point-and-click adventure. While you might enjoy this chick-flick-mimicking romp as a gorgeous animated movie with two likable leads, the dialogue is windy and not nearly as funny as it thinks it is, and the puzzles are thin and predictable. It's not a great way for this charismatic series to go out, and even Runaway veterans will probably be left feeling flat".