Facebook games. Yawn, right? They exist only for tweenage girls and bored office workers who haven't got the sense to notice when they've put down a spreadsheet in order to start playing another spreadsheet (Mafia Dons and vampires do not change that fact).
But they don't have to be that way. With advancements in Flash making ever more complex, multi-player browser games possible (hell, there's a goddamn arena FPS on the way to FB soon), it's totally possible for big game publishers to start bringing their wares to your lunch break.