GameSpy interviewed Irrational's Ken Levine about a wide variety of topics, including the oh-so dreaded BioShock vs System Shock comparison.
From the interview:
GameSpy: In the years since System Shock 2, it's gained a huge cult status among hardcore gamers. Where is your middle ground between satisfying the expectations of that demographic, while making a game that's accessible to gamers who've never played a System Shock, or who are primarily shooter fans?
Ken Levine: If you look at BioShock from a hardcore gamer perspective, it's everything that we wanted both System Shocks to be in terms of visuals and depth; it's just that we didn't have the resources possible back then to do it. I don't know how far you got in the first demo, or with Arcadia, but the amount of depth is where we want it to be. There's the idea, not just of numbers and polygons and what's under the hood, but what you can do in battle.