Harmonix knows music games. Responsible for developing nearly every hit music rhythm game known to man, the studio's credits include Guitar Hero I and II, Frequency, Amplitude, and Karaoke Revolution. Now Harmonix is hard at work developing its most ambitious title yet, Rock Band. Drums, vocals, guitar, and bass will all play together in a single game for the first time this fall. To learn more about this highly anticipated title, IGN went to Alex Rigopulos, co-founder and CEO of Harmonix with questions on everything from the single player game to MIDI possibilities.