Since their adventures in the Shadow Sector in Deadlocked, our heroes have been enjoying some well deserved R&R. Ratchet has been pondering his origins, and his lonely life as the only known Lombax in the universe. Enter Emperor Tachyon, leader of a race of hideous insect-like creatures. He's been obsessed with wiping out the Lombax for centuries and now he's come for everyone's favorite kitten of mass destruction. The Emperor attacks in the opening moments of the game, resulting in a spectacularly explosive introductory level that leaves our heroes stranded in the far-off galaxy of Polaris.