Well, it's not live, but this new episode of the Joystiq Podcast is definitely worth your time. They've got discussion of Batman: Arkham Asylum and the Scribblenauts debacle, a special guest, a code for a free copy of Marvel Vs. Capcom 2 and the greatest email in the history of emails, so you won't want to miss that. Also, now that girls play games, they have one of those too.
So, what are you waiting for? Go feed your ear holes.