BioShock takes place in 1960, but this is not the decade of mop-tops and Beatles that we know of. Oh no, instead you're transported to a place known as Rapture - an underwater civilization that would eventually be of use to all mankind. The trouble is, something has gone horribly wrong here. The corridors and halls of this underwater paradise are deserted and in tatters, and the only people around don't seem to be human, or at least, not any more.
Your only guide through this world is able to vocally communicate with you, leading you where you need to go and explaining what these enemies are that you're coming into contact with. These Splicers, as they're known, are not to be taken lightly. The different types of Splicers are generally named based upon their weapon of choice, like the gun-toting ones who are known as Leadhead Splicers.