Some people have been running "stress tests" to see how Sony's console can handle the program over extended periods. Those people can stop, because they'll be doing that forever. In any case, the PS3-specific questions were answered by SCEA 's Richard Marks (who's doing a stress test himself).
Is it safe to leave the PS3 folding for 24/7?
Yes. There's no indication that the PS3 has problems over long periods of folding... but of course, you should ventilate the darn thing so it won't overheat.
Well... should people give the PS3 a break to cool off?
No. It shouldn't need a cooling period. You know that whirring thing? It's a fan. It regulates the internal temperature.
What's stressed the most and will it affect the stability of the PS3?
The Cell processor. Luckily, it's a high-performance processor built for things just like this. [email protected] shouldn't have any adverse affects on the PlayStation 3's stability.