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'Pac-Man' enzyme eats Alzheimer's plaques

The researchers, from Florida's Mayo Clinic, have worked out how to speed up the activity of a molecule, insulin-degrading enzyme (IDE), which helps chew up the amyloid proteins associated with Alzheimer's in the brain. Their findings are published in PLoS ONE.

IDE is shaped like a clamshell, which opens and shuts, like the videogame character Pac-Man. Amyloid plaques fit inside the 'Pac-Man' enzyme, which then closes, gobbling up the protein inside.

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alzheimers-research.org.uk
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