The Mysterious City: Cairo follows its predecessor The Mysterious City: Golden Prague with a new locale and story. Prague had the advantage of being an unusual place for a hidden object game setting. Egypt, however, is familiar territory for casual games, and you have to wonder why the sequel takes place there after the first game featured such a unique location.
The story is lacking in that there's little to tell. Three artifacts disappear en route to museum in Alexandria, and you must track them down, beginning with the hotel where the delivery person stayed. The story doesn't have much of a mystery except for the names of the two main characters.