Let's drill down and see how the Palm Pre compares with the iPhone and Android's G1.
1. Multitouch touchscreen/gesture control: All three are capacitive, only the Pre and iPhone have multitouch. The Pre's glowy little "gesture area" has dropped the touchable real estate all the way down tto the bottom of the phone, which is great for being able to navigate with one hand and not interfere with the screen at all. The wavey dock you bring up from the bottom looks awesome, but can you use it out of the box without a second thought or page through the manual?
Advantage: iPhone/Pre tossup.