Gamertell has posted a hands-on recount of Resident Evil 5 from Capcom's huge booth at that 2008 Tokyo Game Show.
From the article:
"Capcom definitely enticed many, if not all, Tokyo Game Show attendants with its huge pavilion that included a completely enclosed showcase dedicated to its head runner Resident Evil 5. The showcase was well outfitted and even sported broken windows and peeling paint to add authenticity to its environment. There were four long lines set up, allowing players to choose from single play or cooperative play on the system of their choice - the Xbox 360 or the Playstation 3."
The article sites the game's focus on co-op, two new control schemes and two towns.