''As long as there are people, there will be a long line of medical patients in need of surgery. That's good news for Trauma Center hero, Derek Stiles, as this means plenty of new hospital adventures to be had. Even better, his latest batch of patients in Trauma Center: Under the Knife 2 make for some of the most entertaining operations to date.
Fresh off his operating room duel with the GUILT virus, our master surgeon, Derek, begins Under the Knife 2 in an African region caught up in a civil war. Aided by his lovely assistant, Angie, he's devoted himself to helping as many people as possible in the chaos. This effort ends abruptly, though, as the duo is called back to the US where a new illness known as "PGS" is developing in the same patients who suffered from the GUILT virus in the previous game. From there, the story launches into a series of triumphs, tragedies, and betrayals; and shockingly, it's good. This is due in large part to the intentionally over-dramatic cut-scenes that are rife with humor and keep the adventure light-hearted. The plot brings some heavy, all-too-real issues to the table like tribal conflict in Africa and bioterrorism, but because the game never takes itself too seriously, the story feels fun and won't put you in a bout of depression. There's a surprising amount of narrative for something so straightforward, but it ties together your O.R. sessions nicely and the well-written dialogue will keep you interested throughout.''