DS Fanboy writes: "There's one thing you need to know right up front: Trauma Center: Under the Knife 2 is one of the best DS games to date, even without the benefit of some of the things that were added to the Wii entries in the medical franchise. The gameplay is much improved over the already-excellent first title, and the biggest complaint made by the original's detractors -- the difficulty -- is mitigated here by the inclusion of a range of difficulty settings. The result is pretty close to spectacular.
But when the gameplay is so good that there are few complaints, it's a lot easier to nitpick other aspects of the title, and we've got nitpicks in spades. That's all they are, though: tiny complaints that hardly matter. Under the Knife 2 should be remembered as one of the most satisfying experiences on the DS. Unfortunately, that's not likely to happen."