The Scrub Daily:"A "main" is a preferred character choice. Players usually pick a main to focus on that one fighter, so as not to get bogged down by trying to learn the entire cast. It's better to learn no more than three characters max."
I always chose based on style. If I don't like how the character looks it doesn't matter how high tier he is I don't care! But if I played professionally then I would chose based on tier though.
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