CVG: Four years after the events of Metal Gear Solid 4, the Patriots have been destroyed and the private military companies have collapsed into dozens of smaller factions.
Without Patriot-regulated nanomachines to regulate soldiers' abilities, the PMCs turn to cyborg technology and send half-human super-soldiers onto the battlefield in a world still in the thrall of the war economy. Shoot them and they keep coming, drop a bomb on them and they'll get back up, but slice them in two and there'll be nothing left to fight back.